Filgrastim, a recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, is PEGylated to create Pegfilgrastim. Amgen Inc. originally introduced pegfilgrastim as Neulasta. Pegfilgrastim biosimilars were later introduced to the market. Pegfilgrastim is a supportive oncology medication used to treat neutropenia caused by chemotherapy and/or radiotherapy in cancer patients.
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