Metabolic Stability: A Critical Aspect in Drug Discovery

Health1 months ago

Source: Metabolic Stability: A Critical Aspect in Drug Discovery

Understanding metabolic stability helps to assess pharmacokinetic parameters for determining drug dosingand frequency. Enhancement of the drug’s metabolic stability helps improve patient compliance concerning dosing and dose frequency. Measuring metabolic study by microsomal t1/2 approach combined withthe automated LC-MS/MS and sample pooling strategies delivers reliable data with high-throughput screening.

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